Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0352422
PubChem CID
Molecular Formula
C21H24N4O2
Molecular Weight
364.449 g/mol
Synonyms/Alias
[CHEMBL4475272; BDBM50532003]
InChI Key
IFBJZEMBFDOSNU-UHFFFAOYSA-N
InChI
InChI=1S/C21H24N4O2/c1-15-12-19(25(24-15)17-10-6-3-7-11-17)23-20(26)13-21-22-14-18(27-21)16-8-4-2-5-...
IUPAC Name
N-(2-cyclohexyl-5-methylpyrazol-3-yl)-2-(5-phenyl-13-oxazol-2-yl)acetamide
CAS Number
N/A (Not available)

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

51 54 0 0 0 0 0 0 0 0999 V2000
-1.8958 2.8913 2.8136 C 0 0 0 0 0 0 0 0 0 0 0 0
-1.7375 1.7937 1.8157 C 0 0 0 0 0 0 0 0 0 0 0 0
-2.5674 1.601...

Experimental Data

Activity Data

Target Ion Channel
ATP sensitive inward rectifier potassium channel 10
Uniprot Accession Number
Function
Blocker
Species
Rattus norvegicus (Rat)
IC50
IC50: 31200 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
pH 7.3
Holding Potential
Not specified
Temperature
37 °C
Test Method
Flux assay (Thallium ion)
Test Species
Not specified

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
27
Rotatable Bonds
5
logP
4.5329
Complexity
103.3587
TPSA (Ų)
72.95
H-Bond Donors
1
H-Bond Acceptors
5
Ring Count
4
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